Hypertension September 16, 2024

America’s Hypertension Awareness and Control Problem September 16, 2024

Nearly half of American adults have hypertension, and a new JAMA study reveals that the vast majority of them don’t have their blood pressure under control, while most don’t even know they have the disease. To better understand our hypertension control challenges, a CDC team analyzed 2017-2020 NHANES survey data featuring 7,328 U.S. adults (3,954 […]

Atrial Fibrillation September 12, 2024

AFib Might Be Far More Common Than We Think September 12, 2024

A JACC study suggests that atrial fibrillation is far more prevalent than many previously thought, estimating that nearly one in 20 American adults have been diagnosed with the disease. UCSF researchers analyzed medical records from 29M adults who received hospital-based care in California from 2005 to 2019 (51yr avg. age, 54% women, 50% White), finding […]

Pharmaceuticals September 9, 2024

Questioning Beta-Blocker Interruption After Heart Attack September 9, 2024

Results from the ABYSS trial surprised many at ESC 2024, finding that patients who continue beta-blocker therapy after heart attacks have better long-term outcomes than patients who stop taking the drugs, and they don’t experience the quality of life downsides that some might expect. 

Atrial Fibrillation September 5, 2024

Burn the Ships? What OCEANIC-AF Means for Asundexian and Factor XI September 5, 2024

Nearly a year after Bayer halted its OCEANIC-AF trial, the study’s ESC 2024 presentation revealed new insights into asundexian’s AFib stroke-prevention challenges and what they might mean for Factor XI inhibitors.

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Pharmaceuticals September 3, 2024

Alylam’s Vutrisiran Shines in HELIOS-B Trial September 3, 2024

Alylam’s vutrisiran dominated early ESC 2024 headlines and conversations, after full results from the Phase 3 HELIOS-B trial highlighted its significant impact on transthyretin amyloidosis with cardiomyopathy (ATTR-CM).

Cholesterol Reduction August 29, 2024

Novartis Leqvio’s Case for Broader ASCVD Prevention August 29, 2024

Novartis’ Leqvio took a major step towards establishing itself as an LDL-C monotherapy, after topline results from the V-MONO study revealed significant LDL-C reductions in patients with low or moderate ASCVD risks.

Preventive Cardiology August 26, 2024

Tirzepatide’s Prediabetes and Hypertension Impact August 26, 2024

It looks like we might be able to add prediabetes and hypertension to the growing list of conditions that Eli Lilly’s “weight loss drug” tirzepatide is able to treat, after new analysis of the SURMOUNT-1 trial showed significant reductions in blood pressure and diabetes progression.

Cardiology Business August 22, 2024

J&J Expands Into Interventional HF Treatments With V-Wave Acquisition August 22, 2024

Johnson & Johnson expanded deeper into heart failure and interventional cardiology this week, acquiring interatrial shunt-maker V-Wave for $600M upfront and up to $1.7B with certain milestones.

Pharmaceuticals August 19, 2024

Medicare Drug Cuts Target CVD Meds, Drive Debates August 19, 2024

The White House finally unveiled its negotiated Medicare drug prices, bringing 38%-76% reductions to the first 10 drugs, while drawing mixed industry reactions.

Heart Failure August 15, 2024

Rivus HU6 Shows Obesity-HFpEF Potential August 15, 2024

Rivus Pharmaceuticals’ HU6 is showing promise as a future obesity-related HFpEF treatment, after topline results from its Phase 2a HuMAIN trial revealed valuable weight, symptom, and cardiometabolic improvements - without the risk of muscle loss.

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